San Francisco, CA – October 23, 2013 – July 25th marked the 35th birthday of the world’s first “test tube baby” in the U.K. On the occasion of this significant landmark, the BBC recently visited Pacific Fertility Center (PFC) to get a glimpse of some of the more sophisticated assisted reproductive technologies that have emerged since that time.
PFC Infertility Doctor Blog
The Infertility Blog
KJ was 35 year-old when she presented to PFC after attempting to conceive with her partner for over 2 years. They conceived spontaneously after 14 months, but the baby did not have a heartbeat at the first ultrasound. She subsequently had a miscarriage. Her cycles were regular at 28 day intervals with increasingly heavier flow over the last several months. Her workup included a cycle day 3 follicle stimulating hormone (FSH) of 10 mIU/mL, antral follicle count (AFC) of 8, and an anti-mullerian hormone (AMH) of 0.5 ng/mL. Hysterosalpingogram (HSG, dye test to evaluate the fallopian tubes) revealed open tubes on both sides and a large uterine cavity filling defect. Preovulatory transvaginal ultrasound showed a 8mm endometrial lining whose trilaminar pattern was obscured by a 25mm submucosal fibroid. Semen analysis was normal.
We identify a problem with the sperm in about 30% of couples having infertility treatment. The issues range from having a low sperm count or motility, to having no sperm at all, or even to having sperm that are incapable of fertilizing eggs without significant intervention. The vast majority of these sperm problems can be solved by injecting a single sperm into each egg, using a technique called Intra Cytoplasmic Sperm Injection (ICSI). This works well for sperm with limitations such as poor motility or abnormal morphology (size and shape), and ICSI can be used in conjunction with chemical treatment of the egg in conditions such as gloobozoospermia (round headed sperm) where the sperm need a little help to complete the fertilization process.
San Francisco, CA – October 8th, 2013 – A new technique called in vitro activation (IVA) may for the first time offer hope to certain infertile women, Pacific Fertility Center’s Carl M. Herbert, MD, recently told EveryDay Health, a provider of online health information. Dr. Herbert was commenting on a study published September 30 in the Proceedings of the National Academy of Sciences.
Primo Vision Evo Time-Lapse Embryo Monitoring System with Single Culture Medium
The Primo Vision Time-Lapse Embryo Monitoring System is used during in vitro fertilization (IVF) treatment during embryo incubation to give IVF clinicians the opportunity to observe all embryos as they develop without disturbing them. The system records all moments of embryo development, giving embryologists and physicians an excellent tool for evaluation.
A single culture medium has been developed to allow embryos to remain undisturbed during incubation for up to 6 days while embryologists may continuously monitor them using the Evo time-lapse system.