Microdose Lupron Flare Protocol for IVF - Sample CalendarIn Vitro Fertilization Microflare Protocol
Posted on September 21, 2020 by Inception Fertility
The sample schedule and calendar below is for IVF stimulation using the flare protocol.- The flare protocol is used to "jump start" ovarian response to stimulation in poor responders, in women of advanced reproductive age, and in women with low ovarian reserve.
- As women lose eggs due to aging, it can be hard to stimulate ovaries to produce enough follicles and eggs for a good chance for success with in vitro fertilization.
- This sample in vitro fertilization cycle shows a microdose Lupron flare plan with timing of drugs, ovarian stimulation monitoring, and IVF procedures.
Flare IVF Protocol Calendar
USING BIRTH CONTROL PILLS
Sunday | Monday | Tuesday | Wednesday | Thursday | Friday | Saturday |
---|---|---|---|---|---|---|
1 Birth control pill | 2 Birth control pill | 3 Last birth control pill (of about 14 pills) | 4 No meds | 5 No meds Baseline blood and ultrasound | 6 Start diluted lupron (DL) twice daily | 7 DL twice daily |
8 DL twice daily Start of stimulation shots | 9 DL twice daily Stimulation day 2 | 10 DL twice daily Stimulation day 3 | 11 DL twice daily Stimulation day 4 Blood and ultrasound | 12 DL twice daily Stimulation day 5 | 13 DL twice daily Stimulation day 6 | 14 DL twice daily Stimulation day 3 Blood and ultrasound - follicles now are ready HCG trigger shot at night |
15 | 16 Egg Retrieval Procedure | 17 Fertilization check in morning Start progesterone | 18 | 19 Embryo Transfer Procedure Day 3 transfer of cleavage stage embryos | 20 | 21 Embryo Transfer Procedure Day 5 transfer of blastocyst stage embryos |
22 | 23 | 24 | 25 | 26 | 27 | 28 |
29 | 30 Blood pregnancy test |
Key to flare IVF calendar:
Blood and ultrasound = blood test for IVF hormone values (estrogen levels in IVF stimulation are important) and transvaginal ultrasound to measure the follicle sizes in the ovaries. These visits usually take about 20-30 minutes in our offices and can be scheduled as early as 6:30AM.
DL = diluted Lupron, a subcutaneous injection of a very low dose of Lupron. This drug is taken twice daily starting on the third pill free day (after the last birth control pill).
Stim = ovarian stimulation. Involves subcutaneous injection of a medication containing follicle stimulating hormone (FSH), which causes multiple follicles containing eggs to develop in the ovaries. Ovarian stimulation with a flare usually lasts about 8-11 days.
HCG injection = subcutaneous or intramuscular injection of a medication called HCG, which causes the eggs to complete the maturation process.
Progesterone = vaginal cream or suppositories or intramuscular injection of a medication (female hormone) called progesterone. This drug helps to prepare a receptive uterine lining for embryo implantation.
Egg retrieval procedure = procedure to get eggs from the ovaries
Embryo transfer procedure = procedure to put embryos in the uterus
The example above is a typical flare stimulation cycle. Most patients will need 3 or 4 visits for monitoring the stimulation (shown as "Blood and Ultrasound" on the calendar) before the HCG trigger shot. It depends on the woman's response to the ovarian stimulating medications.
Categories
About the Blog
Welcome to the Pacific Fertility Center Blog! Nationally and internationally recognized for providing exceptional reproductive care, our team believes in empowering people with the knowledge they need to navigate their unique fertility journeys.
From information on the latest fertility treatments to valuable insights on egg donation, surrogacy, and everything in between, the Pacific Fertility Center Blog is your ultimate resource for all things reproductive care and support. Read on to learn more, and contact us today if you have any questions or want to schedule a new patient appointment.