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Microsurgical Epididymal Sperm Aspiration (MESA) is a surgical procedure to remove sperm from the epididymis in men who have an obstruction of the vas deferens or epididymis (or congenital absence of the vas deferens). This procedure is also used for obtaining sperm from men who have had a prior vasectomy. Unlike the TESE procedure, millions of sperm can usually be obtained and excess sperm are frozen for subsequent IVF cycles if needed. The sperm are then injected into the female partner's eggs (see ICSI).

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