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PFC Infertility Doctor Blog

The Infertility Blog

August 26, 2015

San Francisco, CA – August 26, 2015 – Pacific Fertility Center staff presented two scientific posters at the Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), which was held in Lisbon, Portugal, June 14–17, 2015.

Coauthored by Carolyn Givens, MD, and Erin Fischer, Bs, one poster was entitled “Do Anti-Müllerian Hormone (AMH) Levels Predict Outcomes for IVF Patients Undergoing Pre-Implantation Genetic Screening (PGS)?” Anti-Müllerian hormone (AMH) is a protein produced by reproductive tissue that helps give an estimate of the remaining egg supply (ovarian reserve).  

August 21, 2015

Family planning. In many ways, it’s a numbers game. But it’s not just a simple matter of deciding on the number of kids you want and going for it. How early prospective parents start trying makes a world of difference in whether or not they achieve their goals.

Now, researchers have crunched some numbers and created a mathematical model—the first of its kind—to assist couples in building the family they desire. Results of the study appeared in the journal Human Reproduction.1

The researchers designed a computer model to simulate 10,000 couples trying to get pregnant, taking into account a variety of factors such as the likelihood of fertility problems. The model helps predict the age at which a woman should start trying to conceive. Although male fertility also declines with age, this tends to happen after age 60, so the model focuses on female age.

August 13, 2015

These are exciting times for reproductive medicine. New technology is expanding the realm of possibility beyond what was imaginable even just a few decades ago. However, along with new techniques often comes a new round of ethical questions.

Pacific Fertility Center’s insights on one such technology were recently tapped for an article on AUGMENT, developed by OvaScience, a Cambridge-based research company. AUGMENT involves injecting healthy mitochondria—the cells’ energy providers—into aging eggs to improve their quality. According to OvaScience, AUGMENT has led to six live births.

In 2013, the Food and Drug Administration (FDA) required that AUGMENT come under its purview as a new drug. So OvaScience stopped offering AUGMENT in the U.S., and simply went elsewhere.

August 12, 2015

San Francisco, CA – August 12, 2015 – Now that they’re expecting their first child, Mark Zuckerberg and his wife Priscilla Chan are taking the opportunity to raise awareness about a challenge facing many prospective parents: miscarriage. Carolyn Givens, MD, a physician at Pacific Fertility Center and an expert on miscarriage, helped start the conversation through an interview with ABC7 KGO news.

Chan and Zuckerberg, the CEO of Facebook, know about the trials of miscarriage from personal experience. Chan, 30, had three miscarriages during their three-year marriage. By sharing their experience, the Zuckerbergs hope to start a more open dialogue on the topic of miscarriage.

August 10, 2015

A recent Guardian article included an interview with PFC’s Carolyn Givens, MD, on the growing popularity of elective egg freezing among professional women. The article covered much of the waterfront, from financial considerations to ethical, social, and emotional ramifications.