PFC Infertility Doctor Blog

The Infertility Blog

June 26, 2014

San Francisco, CA – June 26, 2014 – Recognized internationally for his expertise as an embryologist and researcher, Joseph Conaghan, PhD, presented at the Irish Fertility Society’s 8th Annual Scientific Meeting in Dublin on May 16 and 17, and at the Third Annual Canadian Embryology Summit in Toronto on May 31. Dr. Conaghan is Clinical Laboratory Director at Pacific Fertility Center.

Founded in 2005, the Irish Fertility Society represents a broad cross section of individuals working in the area of infertility, including doctors, scientists, nurses, counselors, and administrative staff. At its annual meeting, Dr. Conaghan spoke about the use of preimplantation genetic screening (PGS) and time-lapse imaging to promote the wider application of elective single embryo transfer (eSET) with in vitro fertilization (IVF).  

June 25, 2014

Alice and Ted found each other later in life, and at age 38, decided to try building a family. After 6 months of trying to conceive, tests showed Alice was ovulating, had a healthy uterus, patent fallopian tubes, and sperm testing was normal, yet she did not conceive. They pondered what to do next, and asked the question - what is the best treatment for a woman with unexplained infertility in her late 30s?

They read Internet articles about an antiquated way of thinking about treatment for unexplained infertility, beginning with clomiphene and intrauterine insemination (IUI), followed by more intensive ovulation induction with injectable gonadotropins to yield more eggs. Those that were not successful went on to in vitro fertilization (IVF).

June 20, 2014

Irregular ovulation is one of the most common endocrine disorders affecting women of reproductive age leading to abnormal bleeding and infertility.  Causes vary, but by far the largest culprit is a condition called polycystic ovary syndrome (PCOS) especially when the irregular ovulation is accompanied by signs of excessive male hormone production such as upper lip hair or acne.  The prevalence of PCOS is approximately 6-8% in the general population.  Because PCOS is so prevalent, clinicians often overlook the fact that other medical conditions, some with severe health risks, can lead to a similar presentation. 

June 16, 2014

As we approach the 5th decade of the use of in vitro fertilization technology for the treatment of infertility as well as the 4th decade of the use of this technology for the prevention of serious genetic diseases in offspring, we continue to face new scientific frontiers fraught with ethical challenges. One of the latest issues under serious discussion is whether or not we should attempt to manipulate intra-cellular DNA in human eggs.

June 10, 2014

Your best friend may say to you "Relax and you'll get pregnant faster".  This frequently noted advice is the research topic of a recent publication in the journal Human Reproduction by the investigative group LIFE Study.

The LIFE (Longitudinal Investigation of Fertility and the Environment) Study is a project designed to examine the relationship between ubiquitous environmental chemicals, lifestyle, and human fecundity and fertility.  The study comprises of 501 couples recruited prior to attempting pregnancy, who were followed while attempting to become pregnant for up to 12 months of trying.  Of the 501 couples recruited, 401 completed the study, and were followed as they tried to conceive.  All women were between the ages of 18 to 40, were married or partnered, had stopped contraceptives for only up to 2 months and had a male partner at least 18 years old.